ASYMMETRIC-SYNTHESIS OF 3,3-DIPHENYL-2-METHYLALANINE, A NEW UNUSUAL ALPHA-AMINO-ACID FOR PEPTIDES OF BIOLOGICAL INTEREST

Citation
C. Cativiela et al., ASYMMETRIC-SYNTHESIS OF 3,3-DIPHENYL-2-METHYLALANINE, A NEW UNUSUAL ALPHA-AMINO-ACID FOR PEPTIDES OF BIOLOGICAL INTEREST, Tetrahedron, 50(32), 1994, pp. 9837-9846
Citations number
31
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
ISSN journal
00404020
Volume
50
Issue
32
Year of publication
1994
Pages
9837 - 9846
Database
ISI
SICI code
0040-4020(1994)50:32<9837:AO3ANU>2.0.ZU;2-M
Abstract
A strategy of highly stereoselective enolate trapping of lithium lsulf amoylisobornyl-2-cyano-3,3-diphenylpropanoate combined with the approp riate rearrangement process allows the asymmetric synthesis of a novel a-methyl amino acid derived from 3,3-diphenylalanine (Dip).