OBSERVER VARIABILITY IN HISTOPATHOLOGICAL REPORTING OF MALIGNANT BRONCHIAL BIOPSY SPECIMENS

Citation
Ra. Burnett et al., OBSERVER VARIABILITY IN HISTOPATHOLOGICAL REPORTING OF MALIGNANT BRONCHIAL BIOPSY SPECIMENS, Journal of Clinical Pathology, 47(8), 1994, pp. 711-713
Citations number
7
Categorie Soggetti
Pathology
ISSN journal
00219746
Volume
47
Issue
8
Year of publication
1994
Pages
711 - 713
Database
ISI
SICI code
0021-9746(1994)47:8<711:OVIHRO>2.0.ZU;2-6
Abstract
Aims-To histopathologists to classify lung carcinomas on bronchial bio psy material using the current World Health Organisation (WHO) classif ication. Methods-Eleven histopathologists each reviewed 100 randomly s elected bronchial biopsy specimens which had originally been reported as showing lung carcinoma. A single haematoxylin and eosin stained sec tion from each case was circulated and a standard proforma completed. These were analysed using K statistics. Results-The histopathologists were excellent at distinguishing between small cell and non-small-cell carcinoma kappa = 0.86), but not so good at subclassifying the non-sm all cell carcinoma group kappa = 0.25). Conclusions-The clinically imp ortant distinction between small cell and nonsmall cell carcinoma of t he lung is reliably made by competent histopathologists even on Limite d material.