P. Kettle et Tcm. Morris, LATE RELAPSE IN IGD MYELOMA - VALUE OF IMMUNOHISTOCHEMISTRY IN TREPHINE BIOPSY SPECIMENS, Journal of Clinical Pathology, 47(8), 1994, pp. 773-774
IgD myeloma is a rare disorder with a very poor prognosis. An unusual
case is reported where prolonged remission was obtained. Immunohistoch
emical staining of the bone marrow trephine biopsy specimen proved inv
aluable in documenting early relapse. It is suggested that immunohisto
chemistry should be adopted more widely in view of the disparities evi
dent in aspirates and trephines.