Up to a few years ago, patients with cloverleaf skull deformity underw
ent partial surgery to relieve intracranial hypertension with poor fun
ctional and aesthetic results, often leading to relapses and reoperati
ons, both in our own experience and in that of other authors. As of 19
90, however, we started to use the technique described by Persing et a
l. to resolve the complex cloverleaf malformation in a single definiti
ve procedure. Five patients, whose ages ranged from 2 months to 5 year
s, achieved satisfactory results both as regards relief from intracran
ial hypertension and preservation of visual acuity, and from the aesth
etic viewpoint. Surgical approaches and their modifications are descri
bed.