REISSERT COMPOUND STUDIES .67. THE PYRIDO[3,4-B]PYRAZINE REISSERT COMPOUND

Authors
DUARTE FF POPP FD
Citation
Ff. Duarte et Fd. Popp, REISSERT COMPOUND STUDIES .67. THE PYRIDO[3,4-B]PYRAZINE REISSERT COMPOUND, Journal of heterocyclic chemistry, 31(4), 1994, pp. 819-823
Citations number
12
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of heterocyclic chemistry → ACNP
ISSN journal
0022152X
Volume
31
Issue
4
Year of publication
1994
Pages
819 - 823
Database
ISI
SICI code
0022-152X(1994)31:4<819:RCS.TP>2.0.ZU;2-V
Abstract
The pyrido[3,4-b]pyrazine systems investigated were found to form Reis sert compounds in the presence of an acyl halide (or chloroformate) an d trimethylsilyl cyanide. Only the mono Reissert compounds were isolat ed. In the case of 2,3-diphenylpyrido[3,4-b]pyrazine (7), its reaction with benzene sulfonyl chloride and trimethylsilyl cyanide gave 5-cyan o-2,3-diphenylpyrido[3,4-b]pyrazine (16). Alkylation of the Reissert c ompound 11 and analog 12 either directly gave the alkylated hetercycli c base or the alkylated Reissert analog compound.