A. Vazquezbarquero et al., ISOLATED HEADACHE AS THE PRESENTING CLINICAL MANIFESTATION OF INTRACRANIAL TUMORS - A PROSPECTIVE-STUDY, Cephalalgia, 14(4), 1994, pp. 270-272
We prospectively studied over two years the incidence of headache as t
he initial and isolated clinical manifestation of adult patients suffe
ring from intracranial tumors (n = 183). Fifteen patients (8%) exhibit
ed headache as their first and isolated clinical manifestation Age, se
x, neoplasm localization, or pathological diagnosis did not correlate
with the presence of headache. Posterior fossa location and hydrocepha
lus, though not reaching statistical significance, were more frequent
in patients who presented with headache as the first symptom. At the m
oment of diagnosis, 59 (31%) of the patients admitted to headache, tho
ugh only 1 out of the 15 patients starting as headache still had this
symptom as the only manifestation. From our experience in adults, isol
ated headache for longer than 10 weeks will only exceptionally be seco
ndary to an intracranial neoplasm.