THE INFLUENCE OF SOMATOSTATIN ON CALCITONIN SECRETION IN ALBINO-RATS

Authors
GOZARIUSTRIMBU M SANDOR V ORBAI P CUPARENCU B GOZARIU L STRIMBU C LOSASSO C LOFFREDA A LAMPA E
Citation
M. Gozariustrimbu et al., THE INFLUENCE OF SOMATOSTATIN ON CALCITONIN SECRETION IN ALBINO-RATS, Current therapeutic research, 55(8), 1994, pp. 971-975
Citations number
12
Categorie Soggetti
Pharmacology & Pharmacy","Medicine, Research & Experimental
Journal title
Current therapeutic research → ACNP
ISSN journal
0011393X
Volume
55
Issue
8
Year of publication
1994
Pages
971 - 975
Database
ISI
SICI code
0011-393X(1994)55:8<971:TIOSOC>2.0.ZU;2-C
Abstract
The effects of somatostatin on calcitonin secretion were studied in ma le Wistar albino rats. In anesthetized rats, the administration of syn thetic somatostatin induced a reduction in the calcitonin content of t he thyroid. In animals with destroyed central adrenergic neurons, the effects of somatostatin were less visible. An intravenous injection of somatostatin did not affect the baseline calcitonin level, but it did prevent the rise in calcitonin concentration elicited by the intraven ous administration of calcium gluconate.