Headache is one of the cardinal features of intracranial neoplasm. How
ever, there is little published information on the prevalence and clin
ical profiles of headache in patients with brain tumor. This cross-sec
tional study recruited 171 cases of brain tumor. The average age was 3
9 years (range from 4 to 75 years). The female to male ratio was 1.2:1
. The prevalence of headache was 71%. The duration of headache ranged
from 3 days to 10 years with an average of 15.7 months. Most prominent
headache profiles in this series were intermittent, nocturnal and ear
ly morning headache as well as headache upon arising. Most of the pati
ents had mild to moderately severe headache. Headache is more common w
ith tumors below the tentorium cerebelli. It is more prevalent in prim
ary and intracerebral tumor than in metastatic and extracerebral tumor
. Headache has lateralizing value, especially in patients with suprate
ntorial lesions who have no obvious increased intracranial pressure.