585 pregnant women were investigated with both conventional sonographi
c examination and color Doppler examination. The cases with intrauteri
ne growth retardation, preeclampsia, twin pregnancies, congenital malf
ormations and diabetes were excluded. The remaining 550 cases (between
ages 16 and 40) were investigated in the first trimester and gestatio
nal ages were compatible with the last menstrual date. In order to eva
luate fetal development, biparietal diameter, femur length, abdominal
circumference, and estimated fetal weight were calculated by conventio
nal ultrasonographic method. The application of Doppler ultrasound to
the study of fetal umbilical arterial blood flow velocity is a relativ
ely new technique. The failure to obtain useful Doppler signals was ab
out 18-22% with pulse-wave Doppler system. Recently, color Doppler tec
hnology solved this problem. We used an ALOKA 680-SSD ultrasonography
device and color Doppler ultrasonography technique and recorded umbili
cal arterial Doppler signals from every case and calculated classical
Doppler indices - systolic/diastolic (S/D) ratio, pulsatility index (P
I), Pourcelot index or resistive index (RI). Statistical comparisons w
ere made by SPSS program. Correlation coefficient and R(2) values betw
een gestational age and other indices were calculated. The aforementio
ned values were r: -0.79; R(2): 0.63, r: -0.71; R(2): 0.50, r: -0.64;
R(2): 0.41, for S/D, PI, RI, respectively.