We used a single-energy x-ray method and an image processing system to
measure the amount of calcium salts deposited in 60 human aortas (41
male and 19 female) of ages 15-88 y. The aortas were removed at autops
y, slit lengthwise and preserved in formalin. The aortas were x-rayed
while flat, together with a calibration block containing known amounts
of CaHPO4. We determined the amount of calcium salt, referenced to Ca
HPO4, from the x-ray film with a personal computer using a frame-grabb
ing board. There was less calcium in the thoracic than the abdominal a
orta both in males and females and those of ages less than 50 y. The c
oefficient of correlation for abdominal aortic calcium mass versus age
in 19 females was 0.557 and in 41 males was 0.321. The higher correla
tion of mass with age for females may be related to differences in cal
cium metabolism between sexes.