PARAMETERS OF LIPID-PEROXIDATION IN ERYTHROCYTES OF CHILDREN BEING TREATED FOR ACQUIRED SEVERE APLASTIC-ANEMIA

Authors
ZHAROV VN FILLIPOV IK BAKANOV MI KOSHEL IV
Citation
Vn. Zharov et al., PARAMETERS OF LIPID-PEROXIDATION IN ERYTHROCYTES OF CHILDREN BEING TREATED FOR ACQUIRED SEVERE APLASTIC-ANEMIA, Bulletin of experimental biology and medicine, 117(1), 1994, pp. 35-38
Citations number
11
Categorie Soggetti
Medicine, Research & Experimental
Journal title
Bulletin of experimental biology and medicine → ACNP
ISSN journal
00074888
Volume
117
Issue
1
Year of publication
1994
Pages
35 - 38
Database
ISI
SICI code
0007-4888(1994)117:1<35:POLIEO>2.0.ZU;2-9
Abstract
It is shown that a peroxidase-catalase mechanism of antioxidant defens e predominates in the erythrocytes of children with acquired aplastic anemia, and that the high level of lipid peroxidation (LPO) processes in such children dictates the need for continued antioxidant therapy d uring all phases of the disease. The antioxidant effect of glucocortic oids appears to be quite sufficient for eliminating the more severe ef fects of LPO.