EFFECTS OF THE MEMBRANE STABILIZER AJMALINE AND THE LOCAL-ANESTHETIC TRIMECAINE ON THE PHARMACOLOGICAL EFFECTS OF STROPHANTHIN IN-VIVO AND IN-VITRO

Authors
GALENKOYAROSHEVSKII PA LEMKINA SM KOSTIN YV
Citation
Pa. Galenkoyaroshevskii et al., EFFECTS OF THE MEMBRANE STABILIZER AJMALINE AND THE LOCAL-ANESTHETIC TRIMECAINE ON THE PHARMACOLOGICAL EFFECTS OF STROPHANTHIN IN-VIVO AND IN-VITRO, Bulletin of experimental biology and medicine, 117(1), 1994, pp. 61-64
Citations number
10
Categorie Soggetti
Medicine, Research & Experimental
Journal title
Bulletin of experimental biology and medicine → ACNP
ISSN journal
00074888
Volume
117
Issue
1
Year of publication
1994
Pages
61 - 64
Database
ISI
SICI code
0007-4888(1994)117:1<61:EOTMSA>2.0.ZU;2-N
Abstract
Under conditions of simulated circulation failure in rats ajmaline inc reases tolerance for strophanthin cardiotoxicity to a greater extent t han trimecaine. In isolated preparations of frog myocardium both antia rrhythmic agents somewhat weaken the inotropic effect of the cardiac g lycoside and virtually do not influence its chronotropic effect.