DETERMINATION OF THE BIOLOGICAL-ACTIVITY OF CHALONE-CONTAINING PREPARATION FROM EHRLICH ASCITIC CARCINOMA AND ITS FRACTIONS OBTAINED BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY IN A CELL-CULTURE DERIVED FROM THIS TUMOR

Citation
Ds. Gembitskii et al., DETERMINATION OF THE BIOLOGICAL-ACTIVITY OF CHALONE-CONTAINING PREPARATION FROM EHRLICH ASCITIC CARCINOMA AND ITS FRACTIONS OBTAINED BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY IN A CELL-CULTURE DERIVED FROM THIS TUMOR, Bulletin of experimental biology and medicine, 117(1), 1994, pp. 83-86
Citations number
10
Categorie Soggetti
Medicine, Research & Experimental
ISSN journal
00074888
Volume
117
Issue
1
Year of publication
1994
Pages
83 - 86
Database
ISI
SICI code
0007-4888(1994)117:1<83:DOTBOC>2.0.ZU;2-A
Abstract
It is shown that cultured Ehrlich ascitic carcinoma cells are a conven ient test system for the investigation of the effects of various facto rs on DNA synthesis in the cells of this tumor. The application of thi s system markedly facilitates fractionation of a chalone-containing pr eparation, the purpose of this fractionation being the isolation of co mponents affecting specific phases of the mitotic cycle.