The ciliate Ichthyophthirius multifiliis is on economically important
parasite in aqua-culture os well os in the ornamental fish trade. The
parasite has been well studied and details of life cycle, host respons
e and pathogenesis have been characterized Parasite development within
host epithelial tissues initiates localized leukocytic infiltrations,
although the relationship between these responses and host resistance
is uncertain, and whether or not leukocyte responses play a role in p
rotective immunity is unclear Here Frank Cross outlines the character
of localized cellular responses during I, multifiliis infection and di
scusses the contribution of such responses to protective immunity and
pathogenesis.