NEURO-GLIAL HAMARTOMA OF THE SUPRASELLAR CISTERN

A unique case of a suprasellar hamartoma in a 29-year-old woman is pre sented. The lesion was discovered in the context of a work-up for amen orrhea that had lasted 1 year and was resistant to clomiphene and medr oxyprogesterone acetate treatment. Magnetic resonance imaging (MRI) re vealed a 1.2-cm anterior suprasellar lesion with no appearent connecti on to the hypothalamus or hypophysis. She underwent surgical resection of the mass. Pathologic examination revealed randomly arranged mature neurons, glial tissue, and myelinated fibers. There was no evidence o f gonadotropin-releasing hormone producing neurons on immunohistochemi cal studies. Postoperative MRI showed complete resection of the lesion , and 1 year later mensus resumed off medication.