Ah. Abdalla et al., FK-506 AS AN ALTERNATIVE IN CYCLOSPORINE-INDUCED HEMOLYTIC-UREMIC SYNDROME IN A KIDNEY-TRANSPLANT RECIPIENT, Transplant international, 7(5), 1994, pp. 382-384
We describe a patient who received a living related kidney transplant
that worked very well initially but developed oliguria and renal failu
re within 1 week and required dialysis. Clinical and hemological chang
es, as well as renal biopsy, confirmed the diagnosis of cyclosporin-in
duced hemolytic uremic syndrome. The patient did not respond to antire
jection therapy or plasma exchange but did respond to the withdrawal o
f cyclosporin A and the commencement of FK 506.