Background: Posttraumatic endophthalmitis is a rare complication of pe
netrating eye injuries that results in blindness in potentially salvag
eable eyes. Methods: 36 cases of posttraumatic endophthalmitis were ev
aluated retrospectively to determine which factors were associated wit
h visual loss. All cases were treated with intravenous and intraocular
antibiotics. Pars plana vitrectomy was performed in 15 (41.7%) cases
as an adjunct to treatment. Results: Patients ranged in age from 18 mo
nths to 83 years, and included 30 men (83%) and 6 women (17%). Intraoc
ular foreign bodies were present in 6 patients (16.7%), 9 (25%) had co
rneal lacerations, 13 (36.1%) had corneoscleral or scleral lacerations
, and 8 (22.2%) had ocular trauma of unknown type. Of the 36 eyes, 21
(58.3%) had positive culture results, and 10 of these (27.8%) had mult
iple organisms. The most common isolates were Staphylococcus species (
26.5%), Streptococcus species (20.6%), and Bacillus species (14.7%). I
n 4 cases the diagnosis was made 6 or more years after injury. Final v
isual acuity was 20/200 in 8 eyes (22.2%) and 20/300 in 1 eye. In 17 c
ases (47.2%), the eye was salvaged but visual acuity was 5/200 or wors
e, and 10 eyes (27.8%) were lost to enucleation or phthisis bulbi. Con
clusion: Prompt diagnosis and early treatment with intraocular and sys
temic antibiotics are important in the successful management of posttr
aumatic endophthalmitis. The use of pars plana vitrectomy was associat
ed with a good visual outcome when used in select cases.