T. Nagata et al., TISSUE RESIDUES OF SULFADIMETHOXINE FOLLOWING DIETARY ADMINISTRATION TO BROILER-CHICKENS, Journal of veterinary medical science, 56(4), 1994, pp. 795-797
Broilers were divided into four groups and the first group served as t
he control. The second, third and fourth groups were given feed contai
ning 25, 50 and 100 mg/kg of sulfadimethoxine (SDM), respectively, for
21 days, and thereafter each group received the SDM free feed. On cer
tain days during the experiment period, three broilers in each group w
ere sacrificed and tissues, including blood, heart, liver, spleen, giz
zard, thigh muscle, breast muscle and fat, were collected and residual
SDM were determined by HPLC. Two days after withdrawal, SDM in each t
issue had decreased to below the detection limit of 0.01 mug/g.