TISSUE RESIDUES OF SULFADIMETHOXINE FOLLOWING DIETARY ADMINISTRATION TO BROILER-CHICKENS

Broilers were divided into four groups and the first group served as t he control. The second, third and fourth groups were given feed contai ning 25, 50 and 100 mg/kg of sulfadimethoxine (SDM), respectively, for 21 days, and thereafter each group received the SDM free feed. On cer tain days during the experiment period, three broilers in each group w ere sacrificed and tissues, including blood, heart, liver, spleen, giz zard, thigh muscle, breast muscle and fat, were collected and residual SDM were determined by HPLC. Two days after withdrawal, SDM in each t issue had decreased to below the detection limit of 0.01 mug/g.