PURPOSE: To report the spectrum of radiographic findings associated wi
th a new respiratory pathogen: Chlamydia pneumoniae (TWAR strain). MAT
ERIALS AND METHODS: Radiographs of 55 adult patients hospitalized with
serologic evidence of C pneumoniae were retrospectively reviewed. RES
ULTS: On the basis of serologic criteria, two types of acute respirato
ry infection are possible: primary (first exposure) infections and rec
urrent, acute infection in a previously exposed individual. In the pri
mary group, alveolar opacities (65%) with a unilateral distribution (7
1%) were most common at admission. Cavitary disease and hilar or media
stinal lymphadenopathy were uncommon. Small to medium-sized pleural ef
fusions were common in both primary and recurrent groups during hospit
alization. Also, both groups tended to progress to bilateral, mixed, i
nterstitial and alveolar changes during the course of infection. CONCL
USION: Different radiographic patterns exist for the two types of acut
e C pneumoniae infection.