Td. Cherkasova et al., PHOSPHOINOSITIDE METABOLISM IN ENDOTHELIAL-CELLS OF HUMAN UMBILICAL VEIN EFFECTED BY Y-PESTIS TOXIN, Bulletin of experimental biology and medicine, 117(2), 1994, pp. 152-154
Histamine stimulates the metabolism of inositol phosphates and raises
the level of prostacycline in endothelial cells. The activatory effect
of histamine markedly decreases when incubation is performed in the p
resence of PT, whereas the baseline level of phosphoinositide metaboli
tes does not change in endothelial cells.