Nb. Dolzhanskaya et al., EXPRESSION OF THE HUMAN ALPHA-1-ANTITRYPSIN GENE IN HETEROLOGOUS MAMMALIAN-CELLS, Bulletin of experimental biology and medicine, 117(2), 1994, pp. 166-167
A genetic-engineering construction is developed containing the full-si
ze cDNA of human alpha-1-antitrypsin, controlled by the promotor and e
nhancer elements from cytomegalovirus. It is shown that, after transfe
ction with this recombinant DNA, it is properly expressed in heterolog
ous animal cells.