PRODUCTION OF A MURINE MONOCLONAL-ANTIBODY TO THE LOW-INCIDENCE RED-CELL ANTIGEN WR(A) - CHARACTERIZATION AND COMPARISON WITH HUMAN ANTI-WR(A)

Citation
Sm. Ring et al., PRODUCTION OF A MURINE MONOCLONAL-ANTIBODY TO THE LOW-INCIDENCE RED-CELL ANTIGEN WR(A) - CHARACTERIZATION AND COMPARISON WITH HUMAN ANTI-WR(A), Vox sanguinis, 67(2), 1994, pp. 222-225
Citations number
9
Categorie Soggetti
Hematology
Journal title
ISSN journal
00429007
Volume
67
Issue
2
Year of publication
1994
Pages
222 - 225
Database
ISI
SICI code
0042-9007(1994)67:2<222:POAMMT>2.0.ZU;2-N
Abstract
The production of a monoclonal antibody which detects the low-incidenc e red cell antigen Wr(a) is described. The antibody (BGU1-WR) was isol ated following immunization of BALB/tk mice with Wr(a+) cells. BGU1-WR is an IgG1 antibody and reacted in a manner similar to human polyclon al anti-Wr(a) with untreated, protease treated and chemically modified Wr(a+) cells.