PHOTOADDITION OF ALCOHOLS AND ETHERS TO FLAVINS IN THE PRESENCE OF EDTA

Authors
HEELIS PF HARTMAN RF ROSE SD
Citation
Pf. Heelis et al., PHOTOADDITION OF ALCOHOLS AND ETHERS TO FLAVINS IN THE PRESENCE OF EDTA, Tetrahedron letters, 35(33), 1994, pp. 6053-6056
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
33
Year of publication
1994
Pages
6053 - 6056
Database
ISI
SICI code
0040-4039(1994)35:33<6053:POAAET>2.0.ZU;2-D
Abstract
Alcohols and ethers that do not normally photoadd to flavins do so in the presence of EDTA to produce covalent attachment of an alkyl group at C(4a). Thus, irradiation of an aerated solution containing both EDT A and t-butanol resulted in rapid formation of an air-stable, reduced flavin, FlH-C(4a)CH2C(CH3)(2)OH. Similar results were also obtained wi th ethanol, 1-proponol, 2-propanol, pinacol, poly(ethylene glycol), an d dioxane, but nor with methanol or acetone.