NICKEL-CATALYZED 1,4-ADDITION OF ORGANOTITANIUM ATE COMPLEXES TO STERICALLY HINDERED ENONES

Authors
FLEMMING S KABBARA J NICKISCH K NEH H WESTERMANN J
Citation
S. Flemming et al., NICKEL-CATALYZED 1,4-ADDITION OF ORGANOTITANIUM ATE COMPLEXES TO STERICALLY HINDERED ENONES, Tetrahedron letters, 35(33), 1994, pp. 6075-6078
Citations number
21
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
33
Year of publication
1994
Pages
6075 - 6078
Database
ISI
SICI code
0040-4039(1994)35:33<6075:N1OOAC>2.0.ZU;2-1
Abstract
The 1,4-addition of organotitanium ate complexes to enones by nickel c atalysis is reported. With a methyltitanium ate complex good yields of conjugate addition to sterically hindered enones are achieved. Phenyl titanium ate complexes react with less sterically encumbered enones to the 1,4-addition products in moderate to high yields.