H. Saleh et al., UNSUSPECTED METASTATIC RENAL-CELL CARCINOMA DIAGNOSED BY FINE-NEEDLE ASPIRATION BIOPSY - A REPORT OF 4 CASES WITH IMMUNOCYTOCHEMICAL CONTRIBUTIONS, Acta cytologica, 38(4), 1994, pp. 554-561
Fine needle aspiration biopsy (FNAB) is currently considered a valid p
rocedure in the diagnosis of various primary and metastatic neoplasms.
It is also known that computed tomography (CT)-guided percutaneous FN
AB of the kidney is very useful in diagnosing primary renal cell carci
noma (RCC) and has a high accuracy rate. Nonetheless, its usage in the
detection of unsuspected metastatic XCC has been described rarely. Be
low we report four unusual cases of metastatic RCC discovered by FNAB.
The patients presented with subcutaneous, pulmonary, adrenal and flan
k masses with no previous history of ace, Immunocytochemical (ICC) sta
ins, including cytokeratin, epithelial membrane antigen, vimentin and
fat stain, were obtained on two cases and were very helpful in establi
shing the diagnosis, We suggest that cytopathologists consider metasta
tic XCC a possibility when evaluating patients with tumors of unknown
origin and that FNAB can be useful in diagnosing unsuspected metastati
c RCC, especially when assisted by ICC and fat stain.