R. Ashfaq et al., CUTANEOUS ENDOMETRIOSIS AS A DIAGNOSTIC PITFALL OF FINE-NEEDLE ASPIRATION BIOPSY - A REPORT OF 3 CASES, Acta cytologica, 38(4), 1994, pp. 577-581
We describe the cytologic features of three cases of cutaneous endomet
riosis in young women (average age, 27 years); two cases presented as
lower abdominal nodules associated with a previous cesarean section sc
ar. The third case presented as a 5 x 4-cm inguinal mass. The smears w
ere generally cellular, consisting of epithelial and stromal fragments
. Epithelial cells showed large, hyperchromatic nuclei and moderate am
ounts of cytoplasm, with considerable nuclear overlapping. The stromal
aggregates also showed crowded, overlapping nuclei and scant, admired
, hemosiderin-laden macrophages. These features, combined with isolate
d cells in the background, made differentiation from metastatic carcin
oma extremely difficult. Cutaneous endometriosis can present a diagnos
tic pitfall on fine needle aspiration, especially in the absence of a
previous history of abdominal surgery or established diagnosis of endo
metriosis.