An autopsy case of pseudosarcoma in the common bile duct is reported.
An 82-year-old Japanese male complaining of jaundice was admitted to o
ur hospital; he was examined by abdominal ultrasonography (US), reveal
ing biliary calculus, dilatation of the common bile duct, and choledoc
holithiasis, considered to be the possible cause of the obstructive ja
undice. Endoscopic retrograde biliary drainage (ERBD) and cholangiosco
py were performed concurrently, revealing a vaguely whitish tumor near
the papilla of Vater. Two months later, the patient died from complic
ations of the liver, infection, and disseminated intravascular coagula
tion (DIC). An autopsy study revealed tumor cells with extreme pleomor
phic changes, growing diffusely, very like sarcoma. Further examinatio
n revealed epithelioid arrangements in the metastatic lymph node. Twel
ve kinds of immunohistochemical examination showed a positive reaction
, reflecting the presence of an epithelioid cytoskeleton. Of 28 cases
of true and pseudosarcoma of the biliary system reported in the Japane
se literature, only 1 case was reported, in 1990, to involve the commo
n bile duct. We therefore report the present case of pseudosarcoma of
the common bile duct.