S. Nishijima et al., ACTIVITY OF 8 FLUOROQUINOLONES AGAINST METHICILLIN-RESISTANT STAPHYLOCOCCUS-AUREUS ISOLATED FROM CUTANEOUS INFECTIONS, International journal of antimicrobial agents, 4(3), 1994, pp. 147-149
The in vitro susceptibility of methicillin-resistant Staphylococcus au
reus to eight fluoroquinolones, norfloxacin, ofloxacin, enoxacin, cipr
ofloxacin, lomefloxacin, tosufloxacin, sparfloxacin and nadifloxacin,
was evaluated. Methicillin-resistant S. aureus strains were isolated f
rom 64 cutaneous infections from 1991 to 1993. Nadifloxacin exhibited
the lowest MIC among all of the fluoroquinolones. In addition, there w
as no resistance to nadifloxacin. The MIC50 of these drugs has been in
creasing in the past 3 years.