ACTIVITY OF 8 FLUOROQUINOLONES AGAINST METHICILLIN-RESISTANT STAPHYLOCOCCUS-AUREUS ISOLATED FROM CUTANEOUS INFECTIONS

Authors
NISHIJIMA S NAMURA S AKAMATSU H ASADA Y KAWABATA S FUJITA M
Citation
S. Nishijima et al., ACTIVITY OF 8 FLUOROQUINOLONES AGAINST METHICILLIN-RESISTANT STAPHYLOCOCCUS-AUREUS ISOLATED FROM CUTANEOUS INFECTIONS, International journal of antimicrobial agents, 4(3), 1994, pp. 147-149
Citations number
13
Categorie Soggetti
Microbiology,Immunology
Journal title
International journal of antimicrobial agents → ACNP
ISSN journal
09248579
Volume
4
Issue
3
Year of publication
1994
Pages
147 - 149
Database
ISI
SICI code
0924-8579(1994)4:3<147:AO8FAM>2.0.ZU;2-6
Abstract
The in vitro susceptibility of methicillin-resistant Staphylococcus au reus to eight fluoroquinolones, norfloxacin, ofloxacin, enoxacin, cipr ofloxacin, lomefloxacin, tosufloxacin, sparfloxacin and nadifloxacin, was evaluated. Methicillin-resistant S. aureus strains were isolated f rom 64 cutaneous infections from 1991 to 1993. Nadifloxacin exhibited the lowest MIC among all of the fluoroquinolones. In addition, there w as no resistance to nadifloxacin. The MIC50 of these drugs has been in creasing in the past 3 years.