CIS CARBOPLATIN PLUS VINORELBINE +/- RADIOTHERAPY IN STAGE-III AND STAGE-IV NON-SMALL-CELL LUNG-CARCINOMA/

The aim of this study was the retrospective evaluation of the effectiv eness of cis/carboplatin + vinorelbine +/- radiotherapy in 118 patient s with advanced non small cell lung carcinoma (NSCLC). To evaluate the response, pts were divided into three groups: a) Stage III pts. who r eceived both chemotherapy and radiotherapy treatment (RC + RP = 43.75% , median survival 16.25 months); b) Stage III pts. who underwent only CT because RT was contraindicated (RC + RP = 21.95%, median survival 1 2.7 months); c) Stage II pts treated with CT alone (RC + RP = 20%, med ian survival = 12.1 months). Toxicity was mild. The results of the pre sent study, both in terms of response rate and survival, confirm the e ffectiveness of the combination cis/carboplatin + vinorelbine +/- radi otherapy as palliative treatment of advanced NSCLC.