INCIDENCE OVER 3 YEARS OF EXTENDED-SPECTR UM BETA-LACTAMASES IN A GENERAL-HOSPITAL - A RETROSPECTIVE STUDY

A 3 year retrospective study was carried out in the General Hospital o f Perpignan. 198 patients with extended-spectrum beta-lactamases bacil li were studied : 87 were in surgical wards, 62 in medical units, and 49 in long-term care facilities. Mean age was 70 years (97 women and 1 01 men). We found that 49 % of patients came from home, 49,5 % were pr eviously hospitalized in the past 3 years, 84 % were previous given an timicrobial agents, and 86 % previously underwent invasives procedures before infection. The analysis of interval between infection and admi ssion shows that previous hospitalisation is important in regard of ea rly infection (p = 0,01), whereas previous antimicrobial agents use is significantly associates with late infections (p = 0,00001) as well a s invasive procedures (p = 0,0072).