STRUCTURES OF THE BIOXALOMYCINS AND THEIR RELATIONSHIP TO NAPHTHYRIDINOMYCIN

Authors
ZACCARDI J ALLURI M ASHCROFT J BERNAN V KORSHALLA JD MORTON GO SIEGEL M TSAO R WILLIAMS DR MAIESE W ELLESTAD GA
Citation
J. Zaccardi et al., STRUCTURES OF THE BIOXALOMYCINS AND THEIR RELATIONSHIP TO NAPHTHYRIDINOMYCIN, Journal of organic chemistry, 59(15), 1994, pp. 4045-4047
Citations number
15
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of organic chemistry → ACNP
ISSN journal
00223263
Volume
59
Issue
15
Year of publication
1994
Pages
4045 - 4047
Database
ISI
SICI code
0022-3263(1994)59:15<4045:SOTBAT>2.0.ZU;2-G
Abstract
Bioxalomycins alpha 1, alpha 2, beta 1, and beta 2 are novel compounds with potent antimicrobial and antitumor activity isolated from fermen tation broths of Streptomyces viridostaticus. These structures are clo sely related to that of naphthyridinomycin and call into question the published structure of the naturally occurring form of that antitumor antibiotic.