M. Krzyzanowski, METHODS FOR ASSESSING THE EXTENT OF EXPOSURE AND EFFECTS OF AIR-POLLUTION, Occupational and environmental medicine, 54(3), 1997, pp. 145-151
Background and objectives-In many places in Europe, the ambient air po
llution exceeds the levels considered to be safe for health. The objec
tive of the paper is to review and summarise the methods of assessment
of its impact on health, and to indicate the contributions of various
research disciplines, particularly environmental epidemiology. Method
s-The framework for assessment of impact is based on a four stage mode
l: assessment of release of pollutant; assessment of exposure; assessm
ent of the consequence; and risk estimation. Results-Epidemiology is c
rucial in providing the data for the assessment of consequence. The cr
iteria that determine the use of epidemiological studies for this task
include lack of bias, correct control of confounding, and measured es
timates of exposure. At present, those criteria are easier to satisfy
for studies of short term effects on health than for the delayed conse
quences of exposure, or exposure accumulated over a prolonged period.
Combinations of results from various populations through meta-analysis
of existing studies or conducting multicentre studies is often necess
ary to increase the reliability of the consequence assessment stage. C
onclusion-To assess the impact on health systematically helps to focus
on actions to Limit air pollutants with the greatest impacts on human
health and on the most affected populations. This method allows ident
ification of the most pertinent questions which have to be answered by
studies on relations between pollution and health and on exposure of
populations to air pollutants. Epidemiology has considerable potential
to contribute to this research.