U. Salvolini et M. Scarpelli, MRI OF EXCISED HUMAN BRAIN PRELIMINARY TO PATHOLOGICAL EXAMINATION, Bulletin de l'Academie nationale de medecine, 178(3), 1994, pp. 337-345
The purpose of this study was to evaluate the interest of MRI of excis
ed human brains before traditional pathological examination. MRI was p
erformed on 40 formalin fixed brain specimen; the brains were placed o
n tap water in a plastic box, and submitted to standard MRI, 3D FT vol
ume acquisition and multislice SE TI, PD and T2 weighted. The results
of 3D FT volume acquisition were used for multiplanar reconstruction o
f planes according to the direction of anatomical structures. Our expe
rience demonstrate that preliminary MRI of excised brains is possible
because it does not alterate the results of following standard patholo
gical examinations; the dissection may be focused on the MRI demonstra
ted pathology. MRI allows to correlate the results of the pathological
examination of a slice with the state of the whole brain. An interest
ing option is the use of this method for medico-legal purpose.