DETERMINATION OF A NEW RETINOID - 9-CIS RETINOIC ACID IN PLASMA BY HPLC

Authors
MARCHETTI MN BUN H GEIGER JM DURAND A
Citation
Mn. Marchetti et al., DETERMINATION OF A NEW RETINOID - 9-CIS RETINOIC ACID IN PLASMA BY HPLC, Analytical letters, 27(10), 1994, pp. 1847-1862
Citations number
4
Categorie Soggetti
Chemistry Analytical
Journal title
Analytical letters → ACNP
ISSN journal
00032719
Volume
27
Issue
10
Year of publication
1994
Pages
1847 - 1862
Database
ISI
SICI code
0003-2719(1994)27:10<1847:DOANR->2.0.ZU;2-7
Abstract
A method is described for the quantitative analysis of 9-cis retinoic acid in plasma. Following a simple extraction, the compounds are deter mined by reversed-phase high-performance liquid chromatography (HPLC) and detection at 350 nm.This method was applied to plasma specimens co llected from rabbit which received by gorging a single dose administra tion of this compound but it could be applied too to human plasma.