LOCALIZATION OF THE HUMAN CD40 GENE TO CHROMOSOME-20, BANDS Q12-Q13.2

Authors
LAFAGEPOCHITALOFF M HERMAN P BIRG F GALIZZI JP SIMONETTI J MANNONI P BANCHEREAU J
Citation
M. Lafagepochitaloff et al., LOCALIZATION OF THE HUMAN CD40 GENE TO CHROMOSOME-20, BANDS Q12-Q13.2, Leukemia, 8(7), 1994, pp. 1172-1175
Citations number
30
Categorie Soggetti
Hematology,Oncology
Journal title
Leukemia → ACNP
ISSN journal
08876924
Volume
8
Issue
7
Year of publication
1994
Pages
1172 - 1175
Database
ISI
SICI code
0887-6924(1994)8:7<1172:LOTHCG>2.0.ZU;2-O
Abstract
CD40 is a surface glycoprotein, member of the nerve growth factor rece ptor family, which is expressed on B cells and plays an important role in their development, growth, and differentiation. Using chromosomal in situ hybridization, we localized the CD40 gene to the long arm of c hromosome 20, bands q12-q13.2. This localization correlates well with the mapping of the murine CD40 gene to the distal region of chromosome 2, syntenic to the human 20q11-q13 region.