A new method of 3D spatial selection using pulsed quadratic field grad
ients is presented. Like previous pulsed quadratic gradient methods th
e new method requires only two RF pulses to achieve selection in three
dimensions. Unlike previous methods, however, precise alignment of li
near and quadratic gradient coils is not required. This characteristic
allows the method to be used with small or surface quadratic gradient
coils. The method is demonstrated on phantoms and rats.