OCTAHYDRO DERIVATIVES OF A NOVEL HETEROCYCLIC SYSTEM BENZO[F][1,2]DIAZEPINO[5,4,3-C,D]INDOLES

Citation
J. Poikans et al., OCTAHYDRO DERIVATIVES OF A NOVEL HETEROCYCLIC SYSTEM BENZO[F][1,2]DIAZEPINO[5,4,3-C,D]INDOLES, Heterocyclic communications, 3(1), 1997, pp. 73-78
Citations number
9
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
ISSN journal
07930283
Volume
3
Issue
1
Year of publication
1997
Pages
73 - 78
Database
ISI
SICI code
0793-0283(1997)3:1<73:ODOANH>2.0.ZU;2-4
Abstract
The synthesis of benzo[f][1,2]diazepino[5,4,3-c,d]indol-11-ones 4 is d escribed. The structure of the above mentioned compounds has been conf irmed by X-ray crystallographic analysis. The influence of compounds 4 a and 3a on mice behaviour was tested. The results obtained showed tha t compounds 4a and 3a tested at doses of 0.005 to 50.0 mg/kg exerted a slight sedative influence on the CNS.