We report the case of a woman splenectomized to treat her hairy cell l
eukemia (at the moment in remission) 11 years before the detection of
neutropenia. The neutropenia began just after the treatment of pulmona
ry embolism by acenocoumarol. The neutropenia disappeared quickly afte
r substitution of acenocoumarol by fluindione. We discuss the attribut
ion of the neutropenia to acenocoumarol and the part played by hairy c
ell leukemia.