Mjd. Goodfield et al., SHORT-TERM TERBINAFIN THERAPY OF ONYCHOMY COSIS CAUSED BY DERMATOPHYTES, Vestnik dermatologii i venerologii, (3), 1994, pp. 34-37
Terbinafin in daily dose 250 mg was administered to 112 patients with
fungal infections of nails of hands and feet for 12 weeks. The patient
s were followed up for 36 weeks after the treatment. Mycologic cure wa
s attained in 73 % of patients administered the drug and in only 6 % o
f placebo group patients. The treatment had to be discontinued in 2 pa
tients because of terbinafin side effects; rio noticeable deviations w
ere observed in results of laboratory analyses. These results permit a
conclusion on the efficacy and safety of terbinafin 12-week course fo
r patients with nail dermatophytosis.