In Italy, artificial heart development was promoted by virtue of a spe
cial program on technological and industrial development in areas rela
ted to cardiology and cardiosurgery. A first prototype series of elect
romechanical total artificial hearts (TAHs) and ventricular assist dev
ices (VADs), with ball-screw-based actuation technology, has been deve
loped, and preliminary bench tests and short-term animal implant exper
iments were performed. The project started with analysis and developme
nt of existing TAH and VAD models, and it included a fill-sensor-free
control scheme and anatomical fitting studies using a three-dimensiona
l computer model of the chest cavity. Second-generation prototypes are
currently being developed, and they are scheduled for medium-term ben
ch and in vivo testing by early 1994.