Psychological fatigue is defined as a subjectively experienced disincl
ination to continue performing the task at hand. It generally impairs
human efficiency when individuals continue working after they have bec
ome aware of their fatigue. It does not depend on energy expenditure a
nd cannot be measured simply in terms of performance impairment. The i
nteracting causal contributions to fatigue are the length of continuou
s work spells and daily duty periods, time available for rest and cont
inuous sleep, and the arrangement of duty, rest, and sleep periods wit
hin each 24-h cycle. Empirical evidence for the separate and combined
effects of these factors on fatigue, performance decrement, and accide
nt risk are briefly reviewed, and the implications of these findings f
or driving and road safety are considered, with particular reference t
o the professional driver. This study shows that fatigue is insufficie
ntly recognized and reported as a cause of road accidents and that its
effects stem largely from prolonged and irregular working hours, rath
er than simply from time spent at the wheel.