PRESENT AND FUTURE PROJECTS OF THE INTERNATIONAL BREAST-CANCER STUDY-GROUP

The International Breast Cancer Study Group (formerly the Ludwig Group ) has conducted nine clinical trials since 1978 (see the Appendix for participants and authors). Biologic hypotheses related to the combined use of chemotherapy and endocrine therapy in women with operable brea st cancer were tested. Questions of timing of chemotherapy with respec t to tumor surgery and late introduction of chemotherapy were also eva luated. Ongoing and future trials continue in this tradition to invest igate combinations of available endocrine therapies and cytotoxic agen ts.