1,2,3,5,6,7-HEXACHLORONAPHTHALENE AND 1,2,3,4,6,7-HEXACHLORONAPHTHALENE - SELECTIVE RETENTION IN RAT-LIVER AND APPEARANCE IN WILDLIFE

The two isomers 1,2,3,5,6,7- and 1,2,3,4,6,7-hexachloronaphthalene are shown tc be selectively retained in the liver of rats orally dosed wi th the commercial PCN product Halowax 1014. The retention was further studied by dosing rats orally with a mixture of the two compounds. The rats were sacrificed after 1, 10, 35 and 120 days, respectively. The two hexachloronaphthalenes were found to be strongly retained in the l iver and the concentration ratios liver/adipose tissue were remarkably high. 1,2,3,5,6,7 And 1,2,3,4,6,7-hexachloronaphthalene were also fou nd to be present in two environmental samples from the Swedish east co ast, cod liver and guillemot egg.