Tf. Chen et al., INTERMUSCULAR BUPIVACAINE INFUSION FOR CONTROL OF PAIN AFTER RENAL SURGERY - A PRELIMINARY-REPORT, British Journal of Urology, 74(2), 1994, pp. 155-159
Objective To assess the value of continuous bupivacaine wound infusion
for post-operative pain relief after renal surgery. Patients and meth
ods The analgesic efficacy of continuous intermuscular wound infusion
with 0.25% bupivacaine was studied in 10 patients (four men, six women
), with a mean age of 47.5 years (range 25-71) and a mean weight of 71
.2 kg (range 44-99), after renal surgery in a single-blind randomized
trial. The results were compared with those of an age- and weight-matc
hed control group of 10 patients (five men, five women) with a mean ag
e of 47.7 years (range 27-73) and a mean weight of 67.3 kg (range 51-8
5). Post-operative pain was studied objectively by assessing individua
l patient's morphine requirements administered via a patient controlle
d analgesia system, and subjectively with pain scores. Patient mobilit
y was assessed by ward nursing staff using mobility score charts. Resu
lts There was a lower demand for post-operative analgesia in the bupiv
acaine group compared with the control. Although there was no signific
ant difference in the pain scores between the two groups, the bupivaca
ine group was significantly more mobile than the control group after s
urgery. There was no significant difference in the mean post-operative
hospital stay between the two groups. Conclusion Continuous intermusc
ular bupivacaine wound infusion is a simple and safe procedure which l
owers the patients' post-operative analgesic requirements, allows for
earlier mobility and may promote more rapid discharge from hospital.