DIRECT FLUORINATION OF THE ANTHRAQUINONE NUCLEUS - SCOPE AND APPLICATION TO THE SYNTHESIS OF NOVEL RHEIN ANALOGS

Authors
BRUNAVS M DELL CP OWTON WM
Citation
M. Brunavs et al., DIRECT FLUORINATION OF THE ANTHRAQUINONE NUCLEUS - SCOPE AND APPLICATION TO THE SYNTHESIS OF NOVEL RHEIN ANALOGS, Journal of fluorine chemistry, 68(2), 1994, pp. 201-203
Citations number
15
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear
Journal title
Journal of fluorine chemistry → ACNP
ISSN journal
00221139
Volume
68
Issue
2
Year of publication
1994
Pages
201 - 203
Database
ISI
SICI code
0022-1139(1994)68:2<201:DFOTAN>2.0.ZU;2-3
Abstract
Direct fluorination of the functionalised anthraquinone dimethyl rhein methyl ester with Selectfluor(TM) proceeds regioselectively, providin g a concise approach to fluorinated compounds of potential medicinal i nterest. This represents a new use for Selectfluor(TM) which hitherto has only been used for fluorinating relatively activated compounds.