A 13-year-old girl with virginal hypertrophy (bilateral extensive juve
nile hypertrophy) of the breasts is presented. Her breasts began to gr
ow rapidly after puberty and reached an enormous size within a year. O
n examination, both breasts were greatly enlarged. Routine blood chemi
stry and the endocrinological investigations were normal. The computer
ized tomography scan of the sella was unremarkable. A bilateral reduct
ion mammaplasty was performed, and histological analysis of the breast
tissue revealed the diagnosis of virginal hypertrophy. After four mon
ths her breasts began to grow again, and a second mammaplasty was perf
ormed. After this operation, tamoxifen citrate was given to prevent re
currence for four months, and during the follow-up period of 20 months
, no recurrence was noted.