SCALEMIC 12-HYDROXYAMBLIOFURAN AND 12-ACETOXYAMBLIOFURAN, 5 TETRACYCLIC FURANODITERPENES AND A FURANOSESTERTERPENE FROM SPONGIA SP

Authors
SEARLE PA MOLINSKI TF
Citation
Pa. Searle et Tf. Molinski, SCALEMIC 12-HYDROXYAMBLIOFURAN AND 12-ACETOXYAMBLIOFURAN, 5 TETRACYCLIC FURANODITERPENES AND A FURANOSESTERTERPENE FROM SPONGIA SP, Tetrahedron, 50(33), 1994, pp. 9893-9908
Citations number
20
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
50
Issue
33
Year of publication
1994
Pages
9893 - 9908
Database
ISI
SICI code
0040-4020(1994)50:33<9893:S1A15T>2.0.ZU;2-N
Abstract
Eight new compounds were isolated from a Western Australian sponge Spo ngia sp., including 12-hydroxyambliofuran (5), its acetate ester 6, fi ve new tetracyclic diterpenes 7 - 11 and the epoxyfuranosesterterpene carboxylic acid 12. Compounds 5 and 6, each isolated as a 3:1 mixture of enantiomers as determined by a modified Mosher's ester method and c hiral lanthanide NMR shift studies, are rare examples of scalemic mari ne natural products.