IMMUNOELECTRONMICROSCOPIC QUANTITATION OF DIFFERENTIAL LEVELS OF CHLAMYDIAL PROTEINS IN A CELL-CULTURE MODEL OF PERSISTENT CHLAMYDIA-TRACHOMATIS INFECTION
Wl. Beatty et al., IMMUNOELECTRONMICROSCOPIC QUANTITATION OF DIFFERENTIAL LEVELS OF CHLAMYDIAL PROTEINS IN A CELL-CULTURE MODEL OF PERSISTENT CHLAMYDIA-TRACHOMATIS INFECTION, Infection and immunity, 62(9), 1994, pp. 4059-4062
Electron immunolabeling techniques were used for quantitative evaluati
on of alterations in the steady-state levels of chlamydial antigens in
persistent Chlamydia trachomatis cultures. Gamma interferon-mediated
persistent chlamydial development correlated with an increase in the l
evels of the chlamydial heat shock protein (hsp60) and with a signific
ant reduction in the levels of the major outer membrane protein.