APHIDICOLIN SYNTHESIS-(I) - FORMAL SYNTHESIS OF (+ -)-APHIDICOLIN BY THE SUCCESSIVE INTRAMOLECULAR DIELS-ALDER REACTIONS/

Authors
TOYOTA M NISHIKAWA Y SEISHI T FUKUMOTO K
Citation
M. Toyota et al., APHIDICOLIN SYNTHESIS-(I) - FORMAL SYNTHESIS OF (+ -)-APHIDICOLIN BY THE SUCCESSIVE INTRAMOLECULAR DIELS-ALDER REACTIONS/, Tetrahedron, 50(34), 1994, pp. 10183-10192
Citations number
31
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
50
Issue
34
Year of publication
1994
Pages
10183 - 10192
Database
ISI
SICI code
0040-4020(1994)50:34<10183:AS-FSO>2.0.ZU;2-F
Abstract
Formal synthesis of an antitumor and antiviral diterpene aphidicolin ( 1) has been achieved. The key steps, 7-->6 and 4-->3, involve intramol ecular Diels-Alder reaction.