COAGULASE EXPRESSION IN STAPHYLOCOCCUS-AUREUS IS POSITIVELY AND NEGATIVELY MODULATED BY AN AGR-DEPENDENT MECHANISM

Authors
LEBEAU C VANDENESCH F GREENLAND T NOVICK RP ETIENNE J
Citation
C. Lebeau et al., COAGULASE EXPRESSION IN STAPHYLOCOCCUS-AUREUS IS POSITIVELY AND NEGATIVELY MODULATED BY AN AGR-DEPENDENT MECHANISM, Journal of bacteriology, 176(17), 1994, pp. 5534-5536
Citations number
14
Categorie Soggetti
Microbiology
Journal title
Journal of bacteriology → ACNP
ISSN journal
00219193
Volume
176
Issue
17
Year of publication
1994
Pages
5534 - 5536
Database
ISI
SICI code
0021-9193(1994)176:17<5534:CEISIP>2.0.ZU;2-N
Abstract
Expression of staphylocoagulase by agr(+) Staphylococcus aureus depend s on the growth phase, being maximal during exponential growth and dec reasing sharply postexponentially, while an agr-deleted strain continu ously expresses an intermediate level of coagulase. Therefore, coagula se expression appears to be both positively and negatively modulated b y an agr-dependent mechanism.